The personalized intelligent 4D-printed degradable and reconfigurable intestinal stent represents a cutting-edge innovation in the field of interventional medical devices. Fabricated from biodegradable materials via advanced 4D printing technology, it enables personalized customization tailored to the patient’s intestinal structure and lesion characteristics. As the treatment progresses, the stent material naturally degrades in vivo after fulfilling its supporting function, eliminating the need for secondary surgical removal. Its degradation rate matches the repair cycle of intestinal tissue, which not only maintains intestinal patency but also promotes tissue healing and functional reconstruction. This technology paves a brand-new path for the minimally invasive and personalized treatment of complex intestinal diseases such as intestinal obstruction and intestinal fistula.